xCell2
A Tool for Generic Cell Type Enrichment Analysis
Bioconductor version: 3.23 · Package version: 1.4.0
xCell2 provides methods for cell type enrichment analysis using cell type signatures. It includes three main functions - 1. xCell2Train for training custom references objects from bulk or single-cell RNA-seq datasets. 2. xCell2Analysis for conducting the cell type enrichment analysis using the custom reference. 3. xCell2GetLineage for identifying dependencies between different cell types using ontology.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("xCell2") Details
| Maintainer | Almog Angel <almog.angel@campus.technion.ac.il> |
| Author | Almog Angel [aut, cre] (ORCID: <https://orcid.org/0009-0001-3297-6935>), Dvir Aran [aut] (ORCID: <https://orcid.org/0000-0001-6334-5039>) |
| License | GPL (>= 3) |
| URL | https://github.com/AlmogAngel/xCell2 |
| Bug Reports | https://github.com/AlmogAngel/xCell2/issues |
| Downloads rank | 284 |
| Source branch | RELEASE_3_23 |
| biocViews | DifferentialExpression, GeneExpression, GeneSetEnrichment, ImmunoOncology, Microarray, RNASeq, SingleCell, Software, Transcriptomics |
Documentation
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Dependencies
Depends: R (>= 4.0.0)
Imports: SummarizedExperiment, SingleCellExperiment, Rfast, singscore, AnnotationHub, ontologyIndex, tibble, dplyr, BiocParallel, Matrix, minpack.lm, pracma, methods, readr, magrittr, progress, quadprog
Suggests: testthat, knitr, rmarkdown, ggplot2, randomForest, tidyr, EnhancedVolcano, BiocStyle
Reverse dependencies
Suggests Me (1): VISTA