topdownr

Investigation of Fragmentation Conditions in Top-Down Proteomics

Bioconductor version: 3.23 · Package version: 1.34.0

The topdownr package allows automatic and systemic investigation of fragment conditions. It creates Thermo Orbitrap Fusion Lumos method files to test hundreds of fragmentation conditions. Additionally it provides functions to analyse and process the generated MS data and determine the best conditions to maximise overall fragment coverage.

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("topdownr")