ternarynet
Ternary Network Estimation
Bioconductor version: 3.23 · Package version: 1.56.0
Gene-regulatory network (GRN) modeling seeks to infer dependencies between genes and thereby provide insight into the regulatory relationships that exist within a cell. This package provides a computational Bayesian approach to GRN estimation from perturbation experiments using a ternary network model, in which gene expression is discretized into one of 3 states: up, unchanged, or down). The ternarynet package includes a parallel implementation of the replica exchange Monte Carlo algorithm for fitting network models, using MPI.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("ternarynet") Details
| Maintainer | McCall N. Matthew <mccallm@gmail.com> |
| Author | Matthew N. McCall <mccallm@gmail.com>, Anthony Almudevar <Anthony_Alumudevar@urmc.rochester.edu>, David Burton <David_Burton@urmc.rochester.edu>, Harry Stern <harry.stern@rochester.edu> |
| License | GPL (>= 2) |
| Downloads rank | 291 |
| Source branch | RELEASE_3_23 |
| biocViews | Bayesian, CellBiology, GraphAndNetwork, Network, Software |
Documentation
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Dependencies
Depends: R (>= 4.0)
Imports: utils, igraph, methods, graphics, stats, BiocParallel
Suggests: testthat