svaRetro
Retrotransposed transcript detection from structural variants
Bioconductor version: 3.23 · Package version: 1.18.0
svaRetro contains functions for detecting retrotransposed transcripts (RTs) from structural variant calls. It takes structural variant calls in GRanges of breakend notation and identifies RTs by exon-exon junctions and insertion sites. The candidate RTs are reported by events and annotated with information of the inserted transcripts.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("svaRetro") Details
| Maintainer | Ruining Dong <lnyidrn@gmail.com> |
| Author | Ruining Dong [aut, cre] (ORCID: <https://orcid.org/0000-0003-1433-0484>) |
| License | GPL-3 + file LICENSE |
| Bug Reports | https://github.com/PapenfussLab/svaRetro/issues |
| Downloads rank | 258 |
| Source branch | RELEASE_3_23 |
| biocViews | Annotation, Coverage, DataImport, Genetics, Sequencing, Software, VariantAnnotation, VariantDetection |
Documentation
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Dependencies
Depends: GenomicRanges, rtracklayer, BiocGenerics, StructuralVariantAnnotation, R (>= 4.0)
Imports: VariantAnnotation, AnnotationDbi, assertthat, Biostrings, stringr, dplyr, methods, rlang, S4Vectors, Seqinfo, GenomeInfoDb, GenomicFeatures, utils
Suggests: TxDb.Hsapiens.UCSC.hg19.knownGene, org.Hs.eg.db, ggplot2, devtools, testthat (>= 2.1.0), roxygen2, knitr, BiocStyle, plyranges, circlize, tictoc, IRanges, stats, SummarizedExperiment, rmarkdown