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ssPATHS

ssPATHS: Single Sample PATHway Score

Bioconductor version: 3.23 · Package version: 1.26.0

This package generates pathway scores from expression data for single samples after training on a reference cohort. The score is generated by taking the expression of a gene set (pathway) from a reference cohort and performing linear discriminant analysis to distinguish samples in the cohort that have the pathway augmented and not. The separating hyperplane is then used to score new samples.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("ssPATHS")

Details

MaintainerNatalie R. Davidson <natalie.davidson@inf.ethz.ch>
AuthorNatalie R. Davidson
LicenseMIT + file LICENSE
Downloads rank261
Source branchRELEASE_3_23
biocViewsBiomedicalInformatics, Classification, DimensionReduction, GeneExpression, Pathways, RNASeq, Software, Transcriptomics

Documentation

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Dependencies

Depends: R (>= 3.5.0), SummarizedExperiment

Imports: ROCR, dml, MESS

Suggests: ggplot2, testthat (>= 2.1.0)