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spicyR

Spatial analysis of in situ cytometry data

Bioconductor version: 3.23 · Package version: 1.24.0

The spicyR package provides a framework for performing inference on changes in spatial relationships between pairs of cell types for cell-resolution spatial omics technologies. spicyR consists of three primary steps: (i) summarizing the degree of spatial localization between pairs of cell types for each image; (ii) modelling the variability in localization summary statistics as a function of cell counts and (iii) testing for changes in spatial localizations associated with a response variable.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("spicyR")

Details

MaintainerEllis Patrick <ellis.patrick@sydney.edu.au>
AuthorNicolas Canete [aut], Ellis Patrick [aut, cre], Nicholas Robertson [ctb], Alex Qin [ctb], Farhan Ameen [ctb], Shreya Rao [ctb]
LicenseGPL (>=2)
URLhttps://ellispatrick.github.io/spicyR/ https://github.com/SydneyBioX/spicyR, https://sydneybiox.github.io/spicyR/
Bug Reportshttps://github.com/SydneyBioX/spicyR/issues
Downloads rank469
Source branchRELEASE_3_23
biocViewsCellBasedAssays, SingleCell, Software, Spatial

Documentation

Download

Dependencies

Depends: R (>= 4.1)

Imports: BiocParallel, ClassifyR, S4Vectors, SingleCellExperiment, SpatialExperiment, SummarizedExperiment, cli, concaveman, coxme, data.table, dplyr, ggforce, ggh4x, ggnewscale, ggplot2, ggthemes, grDevices, lifecycle, lmerTest, magrittr, methods, pheatmap, rlang, scales, scam, simpleSeg, spatstat.explore, spatstat.geom, stats, survival, tibble, tidyr

Suggests: SpatialDatasets, BiocStyle, knitr, rmarkdown, pkgdown, imcRtools, testthat (>= 3.0.0)

Reverse dependencies

Imports Me (1): lisaClust

Suggests Me (1): Statial