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scRepertoire

A toolkit for single-cell immune receptor profiling

Bioconductor version: 3.23 · Package version: 2.8.0

scRepertoire is a toolkit for processing and analyzing single-cell T-cell receptor (TCR) and immunoglobulin (Ig). The scRepertoire framework supports use of 10x, AIRR, BD, MiXCR, TRUST4, and WAT3R single-cell formats. The functionality includes basic clonal analyses, repertoire summaries, distance-based clustering and interaction with the popular Seurat and SingleCellExperiment/Bioconductor R single-cell workflows.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("scRepertoire")

Details

MaintainerNick Borcherding <ncborch@gmail.com>
AuthorNick Borcherding [aut, cre], Qile Yang [aut], Ksenia Safina [aut], Justin Reimertz [ctb]
LicenseMIT + file LICENSE
URLhttps://www.borch.dev/uploads/scRepertoire/
Bug Reportshttps://github.com/BorchLab/scRepertoire/issues
Downloads rank970
Source branchRELEASE_3_23
biocViewsAnnotation, Classification, ImmunoOncology, Sequencing, SingleCell, Software

Documentation

Download

Dependencies

Depends: ggplot2, R (>= 4.0)

Imports: dplyr, evmix, ggalluvial, ggdendro, ggraph, grDevices, igraph, immApex, iNEXT, Matrix, quantreg, Rcpp, rjson, rlang, S4Vectors, SeuratObject, SingleCellExperiment, SummarizedExperiment, tidygraph, purrr, lifecycle, methods

LinkingTo: Rcpp

Suggests: BiocManager, BiocStyle, circlize, knitr, Peptides, rmarkdown, scales, scater, Seurat, spelling, testthat (>= 3.0.0)

Reverse dependencies

Imports Me (1): Ibex

Suggests Me (3): dandelionR, immApex, immLynx