sSNAPPY
Single Sample directioNAl Pathway Perturbation analYsis
Bioconductor version: 3.23 · Package version: 1.16.0
A single sample pathway perturbation testing method for RNA-seq data. The method propagates changes in gene expression down gene-set topologies to compute single-sample directional pathway perturbation scores that reflect potential direction of change. Perturbation scores can be used to test significance of pathway perturbation at both individual-sample and treatment levels.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("sSNAPPY") Details
| Maintainer | Wenjun Liu <wenjun.liu@adelaide.edu.au> |
| Author | Wenjun Liu [aut, cre] (ORCID: <https://orcid.org/0000-0002-8185-3069>), Stephen Pederson [aut] (ORCID: <https://orcid.org/0000-0001-8197-3303>) |
| License | GPL-3 |
| URL | https://wenjun-liu.github.io/sSNAPPY/ |
| Bug Reports | https://github.com/Wenjun-Liu/sSNAPPY/issues |
| System Requirements | C++11 |
| Downloads rank | 263 |
| Source branch | RELEASE_3_23 |
| biocViews | GeneExpression, GeneSetEnrichment, GeneSignaling, Software |
Documentation
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Dependencies
Depends: R (>= 4.3.0), ggplot2
Imports: dplyr (>= 1.1), magrittr, rlang, stats, graphite, tibble, ggraph, igraph, reshape2, org.Hs.eg.db, SummarizedExperiment, edgeR, methods, ggforce, pheatmap, utils, stringr, gtools, tidyr
Suggests: BiocManager, BiocStyle, colorspace, cowplot, DT, htmltools, knitr, pander, patchwork, rmarkdown, spelling, testthat (>= 3.0.0), tidyverse