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reconsi

Resampling Collapsed Null Distributions for Simultaneous Inference

Bioconductor version: 3.23 · Package version: 1.24.0

Improves simultaneous inference under dependence of tests by estimating a collapsed null distribution through resampling. Accounting for the dependence between tests increases the power while reducing the variability of the false discovery proportion. This dependence is common in genomics applications, e.g. when combining flow cytometry measurements with microbiome sequence counts.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("reconsi")

Details

MaintainerStijn Hawinkel <stijn.hawinkel@psb.ugent.be>
AuthorStijn Hawinkel [cre, aut] (ORCID: <https://orcid.org/0000-0002-4501-5180>)
LicenseGPL-2
Bug Reportshttps://github.com/CenterForStatistics-UGent/reconsi/issues
Downloads rank201
Source branchRELEASE_3_23
biocViewsFlowCytometry, Metagenomics, Microbiome, MultipleComparison, Software

Documentation

Download

Dependencies

Imports: phyloseq, ks, reshape2, ggplot2, stats, methods, graphics, grDevices, matrixStats, Matrix

Suggests: knitr, rmarkdown, testthat