receptLoss

Unsupervised Identification of Genes with Expression Loss in Subsets of Tumors

Bioconductor version: 3.23 · Package version: 1.24.0

receptLoss identifies genes whose expression is lost in subsets of tumors relative to normal tissue. It is particularly well-suited in cases where the number of normal tissue samples is small, as the distribution of gene expression in normal tissue samples is approximated by a Gaussian. Originally designed for identifying nuclear hormone receptor expression loss but can be applied transcriptome wide as well.

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("receptLoss")