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pqsfinder

Identification of potential quadruplex forming sequences

Bioconductor version: 3.23 · Package version: 2.28.0

Pqsfinder detects DNA and RNA sequence patterns that are likely to fold into an intramolecular G-quadruplex (G4). Unlike many other approaches, pqsfinder is able to detect G4s folded from imperfect G-runs containing bulges or mismatches or G4s having long loops. Pqsfinder also assigns an integer score to each hit that was fitted on G4 sequencing data and corresponds to expected stability of the folded G4.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("pqsfinder")

Details

MaintainerJiri Hon <jiri.hon@gmail.com>
AuthorJiri Hon, Dominika Labudova, Matej Lexa and Tomas Martinek
LicenseBSD_2_clause + file LICENSE
URLhttps://pqsfinder.fi.muni.cz
System RequirementsGNU make, C++11
Downloads rank506
Source branchRELEASE_3_23
biocViewsGeneRegulation, MotifDiscovery, SequenceMatching, Software

Documentation

Download

Dependencies

Depends: R (>= 3.5.0), Biostrings

Imports: Rcpp (>= 0.12.3), GenomicRanges, IRanges, S4Vectors, methods

LinkingTo: Rcpp, BH (>= 1.78.0)

Suggests: BiocStyle, knitr, rmarkdown, Gviz, rtracklayer, ggplot2, BSgenome.Hsapiens.UCSC.hg38, testthat, stringr, stringi