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oposSOM

Comprehensive analysis of transcriptome data

Bioconductor version: 3.23 · Package version: 2.30.0

This package translates microarray expression data into metadata of reduced dimension. It provides various sample-centered and group-centered visualizations, sample similarity analyses and functional enrichment analyses. The underlying SOM algorithm combines feature clustering, multidimensional scaling and dimension reduction, along with strong visualization capabilities. It enables extraction and description of functional expression modules inherent in the data.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("oposSOM")

Details

MaintainerHenry Loeffler-Wirth <wirth@izbi.uni-leipzig.de>
AuthorHenry Loeffler-Wirth <wirth@izbi.uni-leipzig.de>, Hoang Thanh Le <le@izbi.uni-leipzig.de> and Martin Kalcher <mkalcher@porkbox.net>
LicenseGPL (>=2)
URLhttp://som.izbi.uni-leipzig.de
Downloads rank390
Source branchRELEASE_3_23
biocViewsDataRepresentation, DifferentialExpression, GeneExpression, GeneSetEnrichment, Software, Visualization

Documentation

Download

Dependencies

Depends: R (>= 4.0.0), igraph (>= 1.0.0)

Imports: fastICA, tsne, scatterplot3d, pixmap, fdrtool, ape, biomaRt, Biobase, RcppParallel, Rcpp, methods, graph, XML, png, RCurl

LinkingTo: RcppParallel, Rcpp