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oncoscanR

Secondary analyses of CNV data (HRD and more)

Bioconductor version: 3.23 · Package version: 1.14.0

The software uses the copy number segments from a text file and identifies all chromosome arms that are globally altered and computes various genome-wide scores. The following HRD scores (characteristic of BRCA-mutated cancers) are included: LST, HR-LOH, nLST and gLOH. the package is tailored for the ThermoFisher Oncoscan assay analyzed with their Chromosome Alteration Suite (ChAS) but can be adapted to any input.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("oncoscanR")

Details

MaintainerYann Christinat <yann.christinat@hcuge.ch>
AuthorYann Christinat [aut, cre], Geneva University Hospitals [aut, cph]
LicenseMIT + file LICENSE
URLhttps://github.com/yannchristinat/oncoscanR
Bug Reportshttps://github.com/yannchristinat/oncoscanR/issues
Downloads rank220
Source branchRELEASE_3_23
biocViewsCopyNumberVariation, Microarray, Software

Documentation

Download

Dependencies

Depends: R (>= 4.2), IRanges (>= 2.30.0), GenomicRanges (>= 1.48.0), magrittr

Imports: readr, S4Vectors, methods, utils

Suggests: testthat (>= 3.1.4), jsonlite, knitr, rmarkdown, BiocStyle