oncoscanR
Secondary analyses of CNV data (HRD and more)
Bioconductor version: 3.23 · Package version: 1.14.0
The software uses the copy number segments from a text file and identifies all chromosome arms that are globally altered and computes various genome-wide scores. The following HRD scores (characteristic of BRCA-mutated cancers) are included: LST, HR-LOH, nLST and gLOH. the package is tailored for the ThermoFisher Oncoscan assay analyzed with their Chromosome Alteration Suite (ChAS) but can be adapted to any input.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("oncoscanR") Details
| Maintainer | Yann Christinat <yann.christinat@hcuge.ch> |
| Author | Yann Christinat [aut, cre], Geneva University Hospitals [aut, cph] |
| License | MIT + file LICENSE |
| URL | https://github.com/yannchristinat/oncoscanR |
| Bug Reports | https://github.com/yannchristinat/oncoscanR/issues |
| Downloads rank | 220 |
| Source branch | RELEASE_3_23 |
| biocViews | CopyNumberVariation, Microarray, Software |
Documentation
Download
Dependencies
Depends: R (>= 4.2), IRanges (>= 2.30.0), GenomicRanges (>= 1.48.0), magrittr
Imports: readr, S4Vectors, methods, utils
Suggests: testthat (>= 3.1.4), jsonlite, knitr, rmarkdown, BiocStyle