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nipalsMCIA

Multiple Co-Inertia Analysis via the NIPALS Method

Bioconductor version: 3.23 · Package version: 1.10.0

Computes Multiple Co-Inertia Analysis (MCIA), a dimensionality reduction (jDR) algorithm, for a multi-block dataset using a modification to the Nonlinear Iterative Partial Least Squares method (NIPALS) proposed in (Hanafi et. al, 2010). Allows multiple options for row- and table-level preprocessing, and speeds up computation of variance explained. Vignettes detail application to bulk- and single cell- multi-omics studies.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("nipalsMCIA")

Details

MaintainerMaximilian Mattessich <maximilian.mattessich@northwestern.edu>
AuthorMaximilian Mattessich [cre] (ORCID: <https://orcid.org/0000-0002-1233-1240>), Joaquin Reyna [aut] (ORCID: <https://orcid.org/0000-0002-8468-2840>), Edel Aron [aut] (ORCID: <https://orcid.org/0000-0002-8683-4772>), Ferhat Ay [aut] (ORCID: <https://orcid.org/0000-0002-0708-6914>), Steven Kleinstein [aut] (ORCID: <https://orcid.org/0000-0003-4957-1544>), Anna Konstorum [aut] (ORCID: <https://orcid.org/0000-0003-4024-2058>)
LicenseGPL-3
URLhttps://github.com/Muunraker/nipalsMCIA
Bug Reportshttps://github.com/Muunraker/nipalsMCIA/issues
Downloads rank228
Source branchRELEASE_3_23
biocViewsClassification, Clustering, MultipleComparison, Normalization, Preprocessing, SingleCell, Software

Documentation

Download

Dependencies

Depends: R (>= 4.3.0)

Imports: ComplexHeatmap, dplyr, fgsea, ggplot2 (>= 3.0.0), graphics, grid, methods, MultiAssayExperiment, SummarizedExperiment, pracma, rlang, RSpectra, scales, stats

Suggests: BiocFileCache, BiocStyle, circlize, ggpubr, KernSmooth, knitr, piggyback, reshape2, rmarkdown, rpart, Seurat (>= 4.0.0), spatstat.explore, stringr, survival, tidyverse, testthat (>= 3.0.0)

Reverse dependencies

Suggests Me (1): tidyexposomics