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mitology

Study of mitochondrial activity from RNA-seq data

Bioconductor version: 3.23 · Package version: 1.4.0

mitology allows to study the mitochondrial activity throught high-throughput RNA-seq data. It is based on a collection of genes whose proteins localize in to the mitochondria. From these, mitology provides a reorganization of the pathways related to mitochondria activity from Reactome and Gene Ontology. Further a ready-to-use implementation of MitoCarta3.0 pathways is included.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("mitology")

Details

MaintainerStefania Pirrotta <stefania.pirrotta@unipd.it>
AuthorStefania Pirrotta [cre, aut] (ORCID: <https://orcid.org/0009-0004-0030-217X>), Enrica Calura [aut, fnd] (ORCID: <https://orcid.org/0000-0001-8463-2432>)
LicenseAGPL-3
URLhttps://github.com/CaluraLab/mitology
Bug Reportshttps://github.com/CaluraLab/mitology/issues
Downloads rank179
Source branchRELEASE_3_23
biocViewsGO, GeneExpression, Pathways, RNASeq, Reactome, SingleCell, Software, Spatial, Visualization

Documentation

Download

Dependencies

Depends: R (>= 4.5.0)

Imports: AnnotationDbi, ape, circlize, clusterProfiler, ComplexHeatmap, ggplot2, ggtree, magrittr, org.Hs.eg.db, ReactomePA, scales

Suggests: Biobase, BiocStyle, GSVA, methods, rmarkdown, knitr, SummarizedExperiment, testthat