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methylscaper

Visualization of Methylation Data

Bioconductor version: 3.23 · Package version: 1.20.0

methylscaper is an R package for processing and visualizing data jointly profiling methylation and chromatin accessibility (MAPit, NOMe-seq, scNMT-seq, nanoNOMe, etc.). The package supports both single-cell and single-molecule data, and a common interface for jointly visualizing both data types through the generation of ordered representational methylation-state matrices. The Shiny app allows for an interactive seriation process of refinement and re-weighting that optimally orders the cells or DNA molecules to discover methylation patterns and nucleosome positioning.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("methylscaper")

Details

MaintainerBacher Rhonda <rbacher@ufl.edu>
AuthorBacher Rhonda [aut, cre], Parker Knight [aut]
LicenseGPL-2
URLhttps://github.com/rhondabacher/methylscaper/
Bug Reportshttps://github.com/rhondabacher/methylscaper/issues
Downloads rank260
Source branchRELEASE_3_23
biocViewsDNAMethylation, Epigenetics, NucleosomePositioning, Sequencing, SingleCell, Software, Visualization

Documentation

Download

Dependencies

Depends: R (>= 4.4.0)

Imports: shiny, shinyjs, seriation, BiocParallel, seqinr, Biostrings, pwalign, Rfast, grDevices, graphics, stats, utils, tools, methods, shinyFiles, data.table, SummarizedExperiment

Suggests: BiocStyle, knitr, rmarkdown, devtools, R.utils