methylclock
Methylclock - DNA methylation-based clocks
Bioconductor version: 3.23 · Package version: 1.18.0
This package allows to estimate chronological and gestational DNA methylation (DNAm) age as well as biological age using different methylation clocks. Chronological DNAm age (in years) : Horvath's clock, Hannum's clock, BNN, Horvath's skin+blood clock, PedBE clock and Wu's clock. Gestational DNAm age : Knight's clock, Bohlin's clock, Mayne's clock and Lee's clocks. Biological DNAm clocks : Levine's clock and Telomere Length's clock.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("methylclock") Details
| Maintainer | Dolors Pelegri-Siso <dolors.pelegri@isglobal.org> |
| Author | Dolors Pelegri-Siso [aut, cre] (ORCID: <https://orcid.org/0000-0002-5993-3003>), Juan R. Gonzalez [aut] (ORCID: <https://orcid.org/0000-0003-3267-2146>) |
| License | MIT + file LICENSE |
| URL | https://github.com/isglobal-brge/methylclock |
| Bug Reports | https://github.com/isglobal-brge/methylclock/issues |
| Downloads rank | 442 |
| Source branch | RELEASE_3_23 |
| biocViews | BiologicalQuestion, DNAMethylation, Normalization, Preprocessing, Software, StatisticalMethod |
Documentation
Download
Dependencies
Depends: R (>= 4.1.0), methylclockData, devtools, quadprog
Imports: Rcpp (>= 1.0.6), ExperimentHub, dplyr, impute, PerformanceAnalytics, Biobase, ggpmisc, tidyverse, ggplot2, ggpubr, minfi, tibble, RPMM, stats, graphics, tidyr, gridExtra, preprocessCore, dynamicTreeCut, planet
LinkingTo: Rcpp