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methyLImp2

Missing value estimation of DNA methylation data

Bioconductor version: 3.23 · Package version: 1.8.0

This package allows to estimate missing values in DNA methylation data. methyLImp method is based on linear regression since methylation levels show a high degree of inter-sample correlation. Implementation is parallelised over chromosomes since probes on different chromosomes are usually independent. Mini-batch approach to reduce the runtime in case of large number of samples is available.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("methyLImp2")

Details

MaintainerAnna Plaksienko <anna@plaxienko.com>
AuthorPietro Di Lena [aut] (ORCID: <https://orcid.org/0000-0002-1838-8918>), Anna Plaksienko [aut, cre] (ORCID: <https://orcid.org/0000-0001-9607-057X>), Claudia Angelini [aut] (ORCID: <https://orcid.org/0000-0001-8350-8464>), Christine Nardini [aut] (ORCID: <https://orcid.org/0000-0001-7601-321X>)
LicenseGPL-3
URLhttps://github.com/annaplaksienko/methyLImp2
Bug Reportshttps://github.com/annaplaksienko/methyLImp2/issues
Downloads rank185
Source branchRELEASE_3_23
biocViewsDNAMethylation, MethylationArray, Microarray, Regression, Software

Documentation

Download

Dependencies

Depends: R (>= 4.3.0), ChAMPdata

Imports: BiocParallel, parallel, stats, methods, corpcor, SummarizedExperiment, utils

Suggests: BiocStyle, knitr, rmarkdown, spelling, testthat (>= 3.0.0)