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methrix

Fast and efficient summarization of generic bedGraph files from Bisufite sequencing

Bioconductor version: 3.23 · Package version: 1.26.0

Bedgraph files generated by Bisulfite pipelines often come in various flavors. Critical downstream step requires summarization of these files into methylation/coverage matrices. This step of data aggregation is done by Methrix, including many other useful downstream functions.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("methrix")

Details

MaintainerAnand Mayakonda <anand_mt@hotmail.com>
AuthorAnand Mayakonda [aut, cre] (ORCID: <https://orcid.org/0000-0003-1162-687X>), Reka Toth [aut] (ORCID: <https://orcid.org/0000-0002-6096-1052>), Rajbir Batra [ctb], Clarissa Feuerstein-Akgöz [ctb], Joschka Hey [ctb], Maximilian Schönung [ctb], Pavlo Lutsik [ctb]
LicenseMIT + file LICENSE
URLhttps://github.com/CompEpigen/methrix
Bug Reportshttps://github.com/CompEpigen/methrix/issues
Downloads rank423
Source branchRELEASE_3_23
biocViewsCoverage, DNAMethylation, Sequencing, Software

Documentation

Download

Dependencies

Depends: R (>= 3.6), data.table (>= 1.12.4), SummarizedExperiment

Imports: rtracklayer, DelayedArray, HDF5Array, BSgenome, DelayedMatrixStats, parallel, methods, ggplot2, S4Vectors, matrixStats, graphics, stats, utils, GenomicRanges, IRanges

Suggests: knitr, rmarkdown, DSS, bsseq, plotly, BSgenome.Mmusculus.UCSC.mm9, MafDb.1Kgenomes.phase3.GRCh38, MafDb.1Kgenomes.phase3.hs37d5, BSgenome.Hsapiens.UCSC.hg19, GenomicScores, Biostrings, RColorBrewer, GenomeInfoDb, testthat (>= 2.1.0)

Reverse dependencies

Suggests Me (1): methFuse