methrix
Fast and efficient summarization of generic bedGraph files from Bisufite sequencing
Bioconductor version: 3.23 · Package version: 1.26.0
Bedgraph files generated by Bisulfite pipelines often come in various flavors. Critical downstream step requires summarization of these files into methylation/coverage matrices. This step of data aggregation is done by Methrix, including many other useful downstream functions.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("methrix") Details
| Maintainer | Anand Mayakonda <anand_mt@hotmail.com> |
| Author | Anand Mayakonda [aut, cre] (ORCID: <https://orcid.org/0000-0003-1162-687X>), Reka Toth [aut] (ORCID: <https://orcid.org/0000-0002-6096-1052>), Rajbir Batra [ctb], Clarissa Feuerstein-Akgöz [ctb], Joschka Hey [ctb], Maximilian Schönung [ctb], Pavlo Lutsik [ctb] |
| License | MIT + file LICENSE |
| URL | https://github.com/CompEpigen/methrix |
| Bug Reports | https://github.com/CompEpigen/methrix/issues |
| Downloads rank | 423 |
| Source branch | RELEASE_3_23 |
| biocViews | Coverage, DNAMethylation, Sequencing, Software |
Documentation
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Dependencies
Depends: R (>= 3.6), data.table (>= 1.12.4), SummarizedExperiment
Imports: rtracklayer, DelayedArray, HDF5Array, BSgenome, DelayedMatrixStats, parallel, methods, ggplot2, S4Vectors, matrixStats, graphics, stats, utils, GenomicRanges, IRanges
Suggests: knitr, rmarkdown, DSS, bsseq, plotly, BSgenome.Mmusculus.UCSC.mm9, MafDb.1Kgenomes.phase3.GRCh38, MafDb.1Kgenomes.phase3.hs37d5, BSgenome.Hsapiens.UCSC.hg19, GenomicScores, Biostrings, RColorBrewer, GenomeInfoDb, testthat (>= 2.1.0)
Reverse dependencies
Suggests Me (1): methFuse