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metapone

Conducts pathway test of metabolomics data using a weighted permutation test

Bioconductor version: 3.23 · Package version: 1.18.0

The package conducts pathway testing from untargetted metabolomics data. It requires the user to supply feature-level test results, from case-control testing, regression, or other suitable feature-level tests for the study design. Weights are given to metabolic features based on how many metabolites they could potentially match to. The package can combine positive and negative mode results in pathway tests.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("metapone")

Details

MaintainerTianwei Yu <yutianwei@cuhk.edu.cn>
AuthorLeqi Tian [aut], Tianwei Yu [aut], Tianwei Yu [cre]
LicenseArtistic-2.0
Downloads rank247
Source branchRELEASE_3_23
biocViewsMassSpectrometry, Metabolomics, Pathways, Software, Technology

Documentation

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Dependencies

Depends: R (>= 4.1.0), BiocParallel, fields, markdown, fdrtool, fgsea, ggplot2, ggrepel

Imports: methods

Suggests: rmarkdown, knitr