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mbQTL

mbQTL: A package for SNP-Taxa mGWAS analysis

Bioconductor version: 3.23 · Package version: 1.12.0

mbQTL is a statistical R package for simultaneous 16srRNA,16srDNA (microbial) and variant, SNP, SNV (host) relationship, correlation, regression studies. We apply linear, logistic and correlation based statistics to identify the relationships of taxa, genus, species and variant, SNP, SNV in the infected host. We produce various statistical significance measures such as P values, FDR, BC and probability estimation to show significance of these relationships. Further we provide various visualization function for ease and clarification of the results of these analysis. The package is compatible with dataframe, MRexperiment and text formats.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("mbQTL")

Details

MaintainerMercedeh Movassagh <mercedeh.movassagh@yale.edu>
AuthorMercedeh Movassagh [aut, cre] (ORCID: <https://orcid.org/0000-0001-7690-0230>), Steven Schiff [aut], Joseph N Paulson [aut]
LicenseMIT + file LICENSE
URL"https://github.com/Mercedeh66/mbQTL"
Downloads rank149
Source branchRELEASE_3_23
biocViewsMetagenomics, Microbiome, Regression, SNP, Software, StatisticalMethod, WholeGenome

Documentation

Download

Dependencies

Depends: R (>= 4.3.0)

Imports: MatrixEQTL, dplyr, ggplot2, readxl, stringr, tidyr, metagenomeSeq, pheatmap, broom, graphics, stats, methods

Suggests: knitr, rmarkdown, BiocStyle