mastR
Markers Automated Screening Tool in R
Bioconductor version: 3.23 · Package version: 1.12.0
mastR is an R package designed for automated screening of signatures of interest for specific research questions. The package is developed for generating refined lists of signature genes from multiple group comparisons based on the results from edgeR and limma differential expression (DE) analysis workflow. It also takes into account the background noise of tissue-specificity, which is often ignored by other marker generation tools. This package is particularly useful for the identification of group markers in various biological and medical applications, including cancer research and developmental biology.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("mastR") Details
| Maintainer | Jinjin Chen <chen.j@wehi.edu.au> |
| Author | Jinjin Chen [aut, cre] (ORCID: <https://orcid.org/0000-0001-7923-5723>), Ahmed Mohamed [aut, ctb] (ORCID: <https://orcid.org/0000-0001-6507-5300>), Chin Wee Tan [ctb] (ORCID: <https://orcid.org/0000-0001-9695-7218>) |
| License | MIT + file LICENSE |
| URL | https://davislaboratory.github.io/mastR |
| Bug Reports | https://github.com/DavisLaboratory/mastR/issues |
| Downloads rank | 266 |
| Source branch | RELEASE_3_23 |
| biocViews | DifferentialExpression, GeneExpression, Software, Transcriptomics, Visualization |
Documentation
- mastR: Simplified Customized Design For Differential Expression Analysis
- mastR: Markers Automated Screening Tool in R
Download
Dependencies
Depends: R (>= 4.3.0)
Imports: AnnotationDbi, Biobase, dplyr, edgeR, ggplot2, ggpubr, graphics, grDevices, GSEABase, limma, Matrix, methods, msigdb, org.Hs.eg.db, patchwork, SeuratObject (> 5.0.0), SingleCellExperiment, stats, SummarizedExperiment, tidyr, utils
Suggests: BiocManager, BiocStyle, clusterProfiler, ComplexHeatmap, depmap, enrichplot, ggrepel, ggvenn, Glimma, gridExtra, jsonlite, knitr, rmarkdown, RobustRankAggreg, rvest, scuttle, singscore, splatter, testthat (>= 3.0.0), UpSetR