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glycoTraitR

Compute and analyze the glycan structrual traits from GPSM data

Bioconductor version: 3.23 · Package version: 1.0.0

GlycoTraitR is an R package for analyzing glycoproteomics data, particularly glycopeptide-spectrum matches (GPSMs). It supports results generated by the pGlyco3 and Glyco-Decipher search engines. The package parses glycan structures, computes monosaccharide compositions and structural traits, and performs differential analysis of glycan heterogeneity. It constructs trait-by-PSM matrices stored in a SummarizedExperiment object, supports user-defined structural motifs, and provides visualization utilities for interpreting glycan trait changes.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("glycoTraitR")

Details

MaintainerBingyuan Zhang <zhang.bingyuan.w8@f.mail.nagoya-u.ac.jp>
AuthorBingyuan Zhang [aut, cre] (ORCID: <https://orcid.org/0000-0002-4892-323X>), Koichi Himori [aut], Yusuke Matsui [aut, fnd]
LicenseMIT + file LICENSE
URLhttps://github.com/matsui-lab/glycoTraitR
Bug Reportshttps://github.com/matsui-lab/glycoTraitR/issues
Downloads rank58
Source branchRELEASE_3_23
biocViewsMassSpectrometry, Proteomics, Software, Visualization

Documentation

Download

Dependencies

Depends: R (>= 4.5.0)

Imports: igraph, SummarizedExperiment, pbapply, car, ggplot2, rlang

Suggests: knitr, BiocStyle, rmarkdown, markdown, testthat (>= 3.0.0)