genomicInstability
Genomic Instability estimation for scRNA-Seq
Bioconductor version: 3.23 · Package version: 1.18.0
This package contain functions to run genomic instability analysis (GIA) from scRNA-Seq data. GIA estimates the association between gene expression and genomic location of the coding genes. It uses the aREA algorithm to quantify the enrichment of sets of contiguous genes (loci-blocks) on the gene expression profiles and estimates the Genomic Instability Score (GIS) for each analyzed cell.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("genomicInstability") Details
| Maintainer | Mariano Alvarez <reef103@gmail.com> |
| Author | Mariano Alvarez [aut, cre], Pasquale Laise [aut], DarwinHealth [cph] |
| License | file LICENSE |
| URL | https://github.com/DarwinHealth/genomicInstability |
| Bug Reports | https://github.com/DarwinHealth/genomicInstability |
| Downloads rank | 229 |
| Source branch | RELEASE_3_23 |
| biocViews | GeneExpression, SingleCell, Software, SystemsBiology |
Documentation
Download
Dependencies
Depends: R (>= 4.1.0), checkmate
Imports: mixtools, SummarizedExperiment
Suggests: SingleCellExperiment, ExperimentHub, pROC