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gcatest

Genotype Conditional Association TEST

Bioconductor version: 3.23 · Package version: 2.12.0

GCAT is an association test for genome wide association studies that controls for population structure under a general class of trait models. This test conditions on the trait, which makes it immune to confounding by unmodeled environmental factors. Population structure is modeled via logistic factors, which are estimated using the `lfa` package.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("gcatest")

Details

MaintainerAlejandro Ochoa <alejandro.ochoa@duke.edu>
AuthorWei Hao [aut], Minsun Song [aut], Alejandro Ochoa [aut, cre] (ORCID: <https://orcid.org/0000-0003-4928-3403>), John D. Storey [aut] (ORCID: <https://orcid.org/0000-0001-5992-402X>)
LicenseGPL (>= 3)
URLhttps://github.com/StoreyLab/gcatest
Bug Reportshttps://github.com/StoreyLab/gcatest/issues
Downloads rank266
Source branchRELEASE_3_23
biocViewsDimensionReduction, GenomeWideAssociation, PrincipalComponent, SNP, Software

Documentation

Download

Dependencies

Depends: R (>= 4.0)

Imports: methods, lfa

Suggests: knitr, rmarkdown, ggplot2, testthat, BEDMatrix, genio

Reverse dependencies

Suggests Me (1): jackstraw