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gDNAx

Diagnostics for assessing genomic DNA contamination in RNA-seq data

Bioconductor version: 3.23 · Package version: 1.10.0

Provides diagnostics for assessing genomic DNA contamination in RNA-seq data, as well as plots representing these diagnostics. Moreover, the package can be used to get an insight into the strand library protocol used and, in case of strand-specific libraries, the strandedness of the data. Furthermore, it provides functionality to filter out reads of potential gDNA origin.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("gDNAx")

Details

MaintainerRobert Castelo <robert.castelo@upf.edu>
AuthorBeatriz Calvo-Serra [aut], Robert Castelo [aut, cre]
LicenseArtistic-2.0
URLhttps://github.com/functionalgenomics/gDNAx
Bug Reportshttps://github.com/functionalgenomics/gDNAx/issues
Downloads rank226
Source branchRELEASE_3_23
biocViewsAlignment, Coverage, DifferentialExpression, FunctionalGenomics, GeneExpression, Preprocessing, RNASeq, Sequencing, Software, SplicedAlignment, Transcription, Transcriptomics

Documentation

Download

Dependencies

Depends: R (>= 4.3)

Imports: methods, BiocGenerics, BiocParallel, matrixStats, Biostrings, S4Vectors, IRanges, Seqinfo, GenomeInfoDb, GenomicRanges, GenomicFiles, GenomicAlignments, GenomicFeatures, Rsamtools, AnnotationHub, RColorBrewer, AnnotationDbi, bitops, plotrix, SummarizedExperiment, grDevices, graphics, stats, utils, cli

Suggests: BiocStyle, knitr, rmarkdown, RUnit, TxDb.Hsapiens.UCSC.hg38.knownGene, gDNAinRNAseqData