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fluentGenomics

A plyranges and tximeta workflow

Bioconductor version: 3.23 · Package version: 1.24.0

An extended workflow using the plyranges and tximeta packages for fluent genomic data analysis. Use tximeta to correctly import RNA-seq transcript quantifications and summarize them to gene counts for downstream analysis. Use plyranges for clearly expressing operations over genomic coordinates and to combine results from differential expression and differential accessibility analyses.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("fluentGenomics")

Details

MaintainerStuart Lee <stuart.andrew.lee@gmail.com>
AuthorStuart Lee [aut, cre] (ORCID: <https://orcid.org/0000-0003-1179-8436>), Michael Love [aut, ctb]
LicenseMIT + file LICENSE
URLhttps://github.com/sa-lee/fluentGenomics
Bug Reportshttps://github.com/sa-lee/fluentGenomics/issues
Downloads rank74
Source branchRELEASE_3_23
biocViewsBasicWorkflow, GeneExpressionWorkflow, Workflow

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Dependencies

Depends: R (>= 4.0)

Imports: plyranges (>= 1.7.7), dplyr, SummarizedExperiment, readr, stats, utils

Suggests: knitr, rmarkdown, bookdown, rappdirs, BiocFileCache, DESeq2, limma, ggplot2, tidyr, tximeta (>= 1.4.2), macrophage (>= 1.2.0)