epialleleR
Fast, Accurate, Epiallele-Aware Methylation Caller and Reporter
Bioconductor version: 3.23 · Package version: 1.20.0
Epialleles are specific DNA methylation patterns that are mitotically and/or meiotically inherited. This package calls and reports cytosine methylation as well as frequencies of hypermethylated epialleles at the level of genomic regions or individual cytosines in next-generation sequencing data using binary alignment map (BAM) files as an input. Among other things, this package can also extract and visualise methylation patterns and assess allele specificity of methylation.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("epialleleR") Details
| Maintainer | Oleksii Nikolaienko <oleksii.nikolaienko@gmail.com> |
| Author | Oleksii Nikolaienko [aut, cre] (ORCID: <https://orcid.org/0000-0002-5910-4934>) |
| License | Artistic-2.0 |
| URL | https://github.com/BBCG/epialleleR |
| Bug Reports | https://github.com/BBCG/epialleleR/issues |
| System Requirements | C++17, GNU make |
| Downloads rank | 292 |
| Source branch | RELEASE_3_23 |
| biocViews | DNAMethylation, Epigenetics, LongRead, MethylSeq, Software |
Documentation
Download
Dependencies
Depends: R (>= 4.1)
Imports: stats, methods, utils, data.table, BiocGenerics, GenomicRanges, Rcpp
Suggests: GenomeInfoDb, SummarizedExperiment, VariantAnnotation, RUnit, knitr, rmarkdown, ggplot2