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ensembldb

Utilities to create and use Ensembl-based annotation databases

Bioconductor version: 3.23 · Package version: 2.36.1

The package provides functions to create and use transcript centric annotation databases/packages. The annotation for the databases are directly fetched from Ensembl using their Perl API. The functionality and data is similar to that of the TxDb packages from the GenomicFeatures package, but, in addition to retrieve all gene/transcript models and annotations from the database, ensembldb provides a filter framework allowing to retrieve annotations for specific entries like genes encoded on a chromosome region or transcript models of lincRNA genes. EnsDb databases built with ensembldb contain also protein annotations and mappings between proteins and their encoding transcripts. Finally, ensembldb provides functions to map between genomic, transcript and protein coordinates.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("ensembldb")

Details

MaintainerJohannes Rainer <johannes.rainer@eurac.edu>
AuthorJohannes Rainer <johannes.rainer@eurac.edu> with contributions from Tim Triche, Sebastian Gibb, Laurent Gatto Christian Weichenberger and Boyu Yu.
LicenseLGPL
URLhttps://github.com/jorainer/ensembldb
Bug Reportshttps://github.com/jorainer/ensembldb/issues
Downloads rank10651
Source branchRELEASE_3_23
biocViewsAnnotationData, Coverage, Genetics, Sequencing, Software

Documentation

Download

Dependencies

Depends: R (>= 3.5.0), BiocGenerics (>= 0.15.10), GenomicRanges (>= 1.61.1), GenomicFeatures (>= 1.61.4), AnnotationFilter (>= 1.5.2)

Imports: methods, RSQLite (>= 1.1), DBI, Biobase, Seqinfo, GenomeInfoDb (>= 1.45.5), AnnotationDbi (>= 1.31.19), rtracklayer (>= 1.69.1), S4Vectors (>= 0.23.10), Rsamtools, IRanges (>= 2.13.24), ProtGenerics, Biostrings (>= 2.77.2), curl

Suggests: BiocStyle, knitr, EnsDb.Hsapiens.v86 (>= 0.99.8), testthat, BSgenome.Hsapiens.NCBI.GRCh38, ggbio (>= 1.24.0), Gviz (>= 1.20.0), rmarkdown, AnnotationHub

Enhances: RMariaDB, shiny

Reverse dependencies

Depends On Me (10): AHEnsDbs, chimeraviz, demuxSNP, EnsDb.Hsapiens.v75, EnsDb.Hsapiens.v79, EnsDb.Hsapiens.v86, EnsDb.Mmusculus.v75, EnsDb.Mmusculus.v79, EnsDb.Rnorvegicus.v75, EnsDb.Rnorvegicus.v79

Imports Me (27): biovizBase, BUSpaRse, cellGeometry, chevreulProcess, ChIPpeakAnno, CleanUpRNAseq, damidBind, diffUTR, drugTargetInteractions, epimutacions, epivizrData, GenomicDistributionsData, ggbio, GRaNIE, Gviz, locuszoomr, RAIDS, revert, RITAN, RNAseqQC, scanMiRApp, scFeatures, scRNAseq, signifinder, singleCellTK, TVTB, tximeta

Suggests Me (18): AlphaMissenseR, AnnotationHub, autonomics, celldex, CNVRanger, eisaR, EpiTxDb, fishpond, gaawr2, GenomicFeatures, GRIN2, ldblock, multicrispr, nullranges, pQTLdata, satuRn, txdbmaker, wiggleplotr