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drugfindR

Investigate iLINCS for candidate repurposable drugs

Bioconductor version: 3.23 · Package version: 1.0.0

This package provides a convenient way to access the LINCS Signatures available in the iLINCS database. These signatures include Consensus Gene Knockdown Signatures, Gene Overexpression signatures and Chemical Perturbagen Signatures. It also provides a way to enter your own transcriptomic signatures and identify concordant and discordant signatures in the LINCS database.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("drugfindR")

Details

MaintainerAli Sajid Imami <Ali.Sajid.Imami@gmail.com>
AuthorAli Sajid Imami [aut, cre] (ORCID: <https://orcid.org/0000-0003-3684-3539>), Smita Sahay [aut] (ORCID: <https://orcid.org/0009-0003-4377-8963>), Justin Fortune Creeden [aut] (ORCID: <https://orcid.org/0000-0003-3123-8401>), Robert Erne McCullumsmith [ctb, fnd] (ORCID: <https://orcid.org/0000-0001-6921-7150>)
LicenseGPL-3 + file LICENSE
URLhttps://github.com/CogDisResLab/drugfindR, https://cogdisreslab.github.io/drugfindR/
Bug Reportshttps://github.com/CogDisResLab/drugfindR/issues
Downloads rank69
Source branchRELEASE_3_23
biocViewsDifferentialExpression, FunctionalPrediction, GeneSetEnrichment, Network, SingleCell, Software

Documentation

Download

Dependencies

Depends: R (>= 4.5.0)

Imports: tibble, rlang, dplyr, purrr, readr, stringr, stats, lifecycle, S4Vectors, httr2, curl, DFplyr

Suggests: AnnotationDbi, BiocStyle, biocthis, codemetar, devtools, here, httptest2, jsonlite, knitr, rmarkdown, testthat (>= 3.0.0), tidyverse, usethis