demuxmix
Demultiplexing oligo-barcoded scRNA-seq data using regression mixture models
Bioconductor version: 3.23 · Package version: 1.14.0
A package for demultiplexing single-cell sequencing experiments of pooled cells labeled with barcode oligonucleotides. The package implements methods to fit regression mixture models for a probabilistic classification of cells, including multiplet detection. Demultiplexing error rates can be estimated, and methods for quality control are provided.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("demuxmix") Details
| Maintainer | Hans-Ulrich Klein <hansulrich.klein@gmail.com> |
| Author | Hans-Ulrich Klein [aut, cre] (ORCID: <https://orcid.org/0000-0002-6382-9428>) |
| License | Artistic-2.0 |
| URL | https://github.com/huklein/demuxmix |
| Bug Reports | https://github.com/huklein/demuxmix/issues |
| Downloads rank | 251 |
| Source branch | RELEASE_3_23 |
| biocViews | Classification, Preprocessing, Regression, Sequencing, SingleCell, Software |
Documentation
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Dependencies
Depends: R (>= 4.0.0)
Imports: stats, MASS, Matrix, ggplot2, gridExtra, methods
Suggests: BiocStyle, cowplot, DropletUtils, knitr, reshape2, rmarkdown, testthat (>= 3.0.0)
Reverse dependencies
Imports Me (1): demuxSNP