cytofQC
Labels normalized cells for CyTOF data and assigns probabilities for each label
Bioconductor version: 3.23 · Package version: 2.0.0
cytofQC is a package for initial cleaning of CyTOF data. It uses a semi-supervised approach for labeling cells with their most likely data type (bead, doublet, debris, dead) and the probability that they belong to each label type. This package does not remove data from the dataset, but provides labels and information to aid the data user in cleaning their data. Our algorithm is able to distinguish between doublets and large cells.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("cytofQC") Details
| Maintainer | Jill Lundell <jflundell@gmail.com> |
| Author | Jill Lundell [aut, cre] (ORCID: <https://orcid.org/0000-0002-6048-4700>), Kelly Street [aut] (ORCID: <https://orcid.org/0000-0001-6379-5013>) |
| License | Artistic-2.0 |
| URL | https://github.com/jillbo1000/cytofQC |
| Bug Reports | https://github.com/jillbo1000/cytofQC/issues |
| Downloads rank | 177 |
| Source branch | RELEASE_3_23 |
| biocViews | Annotation, SingleCell, Software |
Documentation
Download
Dependencies
Imports: CATALYST, flowCore, e1071, EZtune, gbm, ggplot2, matrixStats, randomForest, rmarkdown, SingleCellExperiment, stats, SummarizedExperiment, ssc, S4Vectors, graphics, methods, mixtools
Suggests: gridExtra, knitr, RColorBrewer, testthat, uwot