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censcyt

Differential abundance analysis with a right censored covariate in high-dimensional cytometry

Bioconductor version: 3.23 · Package version: 1.20.0

Methods for differential abundance analysis in high-dimensional cytometry data when a covariate is subject to right censoring (e.g. survival time) based on multiple imputation and generalized linear mixed models.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("censcyt")

Details

MaintainerReto Gerber <gerberreto@pm.me>
AuthorReto Gerber [aut, cre] (ORCID: <https://orcid.org/0000-0001-5414-8906>)
LicenseMIT + file LICENSE
URLhttps://github.com/retogerber/censcyt
Bug Reportshttps://github.com/retogerber/censcyt/issues
Downloads rank250
Source branchRELEASE_3_23
biocViewsCellBasedAssays, CellBiology, Clustering, FeatureExtraction, FlowCytometry, ImmunoOncology, Proteomics, SingleCell, Software, Survival

Documentation

Download

Dependencies

Depends: R (>= 4.0), diffcyt

Imports: BiocParallel, broom.mixed, dirmult, dplyr, edgeR, fitdistrplus, lme4, magrittr, MASS, methods, mice, multcomp, purrr, rlang, S4Vectors, stats, stringr, SummarizedExperiment, survival, tibble, tidyr, utils

Suggests: BiocStyle, knitr, rmarkdown, testthat, ggplot2