biosigner
Signature discovery from omics data
Bioconductor version: 3.23 · Package version: 1.40.0
Feature selection is critical in omics data analysis to extract restricted and meaningful molecular signatures from complex and high-dimension data, and to build robust classifiers. This package implements a new method to assess the relevance of the variables for the prediction performances of the classifier. The approach can be run in parallel with the PLS-DA, Random Forest, and SVM binary classifiers. The signatures and the corresponding 'restricted' models are returned, enabling future predictions on new datasets. A Galaxy implementation of the package is available within the Workflow4metabolomics.org online infrastructure for computational metabolomics.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("biosigner") Details
| Maintainer | Etienne A. Thevenot <etienne.thevenot@cea.fr> |
| Author | Philippe Rinaudo [aut], Etienne A. Thevenot [aut, cre] (ORCID: <https://orcid.org/0000-0003-1019-4577>) |
| License | CeCILL |
| URL | http://dx.doi.org/10.3389/fmolb.2016.00026 |
| Downloads rank | 344 |
| Source branch | RELEASE_3_23 |
| biocViews | Classification, FeatureExtraction, Lipidomics, MassSpectrometry, Metabolomics, Proteomics, Software, Transcriptomics |
Documentation
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Dependencies
Imports: Biobase, methods, e1071, grDevices, graphics, MultiAssayExperiment, MultiDataSet, randomForest, ropls, stats, SummarizedExperiment, utils
Suggests: BiocGenerics, BiocStyle, golubEsets, hu6800.db, knitr, omicade4, rmarkdown, testthat
Reverse dependencies
Suggests Me (1): phenomis