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biosigner

Signature discovery from omics data

Bioconductor version: 3.23 · Package version: 1.40.0

Feature selection is critical in omics data analysis to extract restricted and meaningful molecular signatures from complex and high-dimension data, and to build robust classifiers. This package implements a new method to assess the relevance of the variables for the prediction performances of the classifier. The approach can be run in parallel with the PLS-DA, Random Forest, and SVM binary classifiers. The signatures and the corresponding 'restricted' models are returned, enabling future predictions on new datasets. A Galaxy implementation of the package is available within the Workflow4metabolomics.org online infrastructure for computational metabolomics.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("biosigner")

Details

MaintainerEtienne A. Thevenot <etienne.thevenot@cea.fr>
AuthorPhilippe Rinaudo [aut], Etienne A. Thevenot [aut, cre] (ORCID: <https://orcid.org/0000-0003-1019-4577>)
LicenseCeCILL
URLhttp://dx.doi.org/10.3389/fmolb.2016.00026
Downloads rank344
Source branchRELEASE_3_23
biocViewsClassification, FeatureExtraction, Lipidomics, MassSpectrometry, Metabolomics, Proteomics, Software, Transcriptomics

Documentation

Download

Dependencies

Imports: Biobase, methods, e1071, grDevices, graphics, MultiAssayExperiment, MultiDataSet, randomForest, ropls, stats, SummarizedExperiment, utils

Suggests: BiocGenerics, BiocStyle, golubEsets, hu6800.db, knitr, omicade4, rmarkdown, testthat

Reverse dependencies

Suggests Me (1): phenomis