anglemania

Feature Extraction for scRNA-seq Dataset Integration

Bioconductor version: 3.23 · Package version: 1.2.0

anglemania extracts genes from multi-batch scRNA-seq experiments for downstream dataset integration. It shows improvement over the conventional usage of highly-variable genes for many integration tasks. We leverage gene-gene correlations that are stable across batches to identify biologically informative genes which are less affected by batch effects. Currently, its main use is for single-cell RNA-seq dataset integration, but it can be applied for other multi-batch downstream analyses such as NMF.

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("anglemania")