aggregateBioVar

Differential Gene Expression Analysis for Multi-subject scRNA-seq

Bioconductor version: 3.23 · Package version: 1.22.0

For single cell RNA-seq data collected from more than one subject (e.g. biological sample or technical replicates), this package contains tools to summarize single cell gene expression profiles at the level of subject. A SingleCellExperiment object is taken as input and converted to a list of SummarizedExperiment objects, where each list element corresponds to an assigned cell type. The SummarizedExperiment objects contain aggregate gene-by-subject count matrices and inter-subject column metadata for individual subjects that can be processed using downstream bulk RNA-seq tools.

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("aggregateBioVar")