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TSCAN

Tools for Single-Cell Analysis

Bioconductor version: 3.23 · Package version: 1.50.0

Provides methods to perform trajectory analysis based on a minimum spanning tree constructed from cluster centroids. Computes pseudotemporal cell orderings by mapping cells in each cluster (or new cells) to the closest edge in the tree. Uses linear modelling to identify differentially expressed genes along each path through the tree. Several plotting and interactive visualization functions are also implemented.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("TSCAN")

Details

MaintainerZhicheng Ji <zji4@jhu.edu>
AuthorZhicheng Ji [aut, cre], Hongkai Ji [aut], Aaron Lun [ctb]
LicenseGPL(>=2)
Downloads rank808
Source branchRELEASE_3_23
biocViewsGUI, GeneExpression, Software, Visualization

Documentation

Download

Dependencies

Depends: R (>= 4.4.0), SingleCellExperiment, TrajectoryUtils

Imports: ggplot2, shiny, plyr, grid, fastICA, igraph, combinat, mgcv, mclust, gplots, methods, stats, Matrix, SummarizedExperiment, SparseArray (>= 1.5.23), DelayedArray (>= 0.31.9), S4Vectors

Suggests: knitr, testthat, scuttle, scran, metapod, BiocParallel, BiocNeighbors, batchelor

Reverse dependencies

Imports Me (3): DIscBIO, FEAST, singleCellTK

Suggests Me (1): condiments