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TADCompare

TADCompare: Identification and characterization of differential TADs

Bioconductor version: 3.23 · Package version: 1.22.0

TADCompare is an R package designed to identify and characterize differential Topologically Associated Domains (TADs) between multiple Hi-C contact matrices. It contains functions for finding differential TADs between two datasets, finding differential TADs over time and identifying consensus TADs across multiple matrices. It takes all of the main types of HiC input and returns simple, comprehensive, easy to analyze results.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("TADCompare")

Details

MaintainerMikhail Dozmorov <mikhail.dozmorov@gmail.com>
AuthorMikhail Dozmorov [aut, cre] (ORCID: <https://orcid.org/0000-0002-0086-8358>), Kellen Cresswell [aut]
LicenseMIT + file LICENSE
URLhttps://github.com/dozmorovlab/TADCompare
Bug Reportshttps://github.com/dozmorovlab/TADCompare/issues
Downloads rank275
Source branchRELEASE_3_23
biocViewsClustering, FeatureExtraction, HiC, Sequencing, Software

Documentation

Download

Dependencies

Depends: R (>= 4.0)

Imports: dplyr, PRIMME, cluster, Matrix, magrittr, HiCcompare, ggplot2, tidyr, ggpubr, RColorBrewer, reshape2, cowplot

Suggests: BiocStyle, knitr, rmarkdown, microbenchmark, testthat, covr, pheatmap, SpectralTAD, magick, qpdf