Bioc2026 Registration Open!

SpatialDecon

Deconvolution of mixed cells from spatial and/or bulk gene expression data

Bioconductor version: 3.23 · Package version: 1.22.0

Using spatial or bulk gene expression data, estimates abundance of mixed cell types within each observation. Based on "Advances in mixed cell deconvolution enable quantification of cell types in spatial transcriptomic data", Danaher (2022). Designed for use with the NanoString GeoMx platform, but applicable to any gene expression data.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("SpatialDecon")

Details

MaintainerMaddy Griswold <mgriswold@nanostring.com>
AuthorMaddy Griswold [cre, aut], Patrick Danaher [aut]
LicenseMIT + file LICENSE
Bug Reportshttps://github.com/Nanostring-Biostats/SpatialDecon/issues
Downloads rank409
Source branchRELEASE_3_23
biocViewsFeatureExtraction, GeneExpression, ImmunoOncology, Software, Spatial, Transcriptomics

Documentation

Download

Dependencies

Depends: R (>= 4.0.0)

Imports: grDevices, stats, utils, graphics, SeuratObject, Biobase, GeomxTools, repmis, methods, Matrix, logNormReg (>= 0.4)

Suggests: testthat, knitr, rmarkdown, qpdf, Seurat

Reverse dependencies

Suggests Me (1): GeomxTools