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Site2Target

An R package to associate peaks and target genes

Bioconductor version: 3.23 · Package version: 1.4.0

Statistics implemented for both peak-wise and gene-wise associations. In peak-wise associations, the p-value of the target genes of a given set of peaks are calculated. Negative binomial or Poisson distributions can be used for modeling the unweighted peaks targets and log-nromal can be used to model the weighted peaks. In gene-wise associations a table consisting of a set of genes, mapped to specific peaks, is generated using the given rules.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("Site2Target")

Details

MaintainerPeyman Zarrineh <peyman.zarrineh@manchester.ac.uk>
AuthorPeyman Zarrineh [cre, aut] (ORCID: <https://orcid.org/0000-0003-4820-4101>)
LicenseGPL-2
Bug Reportshttps://github.com/fls-bioinformatics-core/Site2Target/issues
Downloads rank144
Source branchRELEASE_3_23
biocViewsAnnotation, ChIPSeq, Epigenetics, GeneExpression, GeneTarget, Software

Documentation

Download

Dependencies

Depends: R (>= 4.4)

Imports: S4Vectors, stats, utils, BiocGenerics, GenomeInfoDb, MASS, IRanges, GenomicRanges

Suggests: BiocStyle, knitr, rmarkdown, testthat (>= 3.0.0)