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Single.mTEC.Transcriptomes

Single Cell Transcriptome Data and Analysis of Mouse mTEC cells

Bioconductor version: 3.23 · Package version: 1.40.0

This data package contains the code used to analyse the single-cell RNA-seq and the bulk ATAC-seq data from the manuscript titled: Single-cell transcriptome analysis reveals coordinated ectopic-gene expression patterns in medullary thymic epithelial cells. This paper was published in Nature Immunology 16,933-941(2015). The data objects provided in this package has been pre-processed: the raw data files can be downloaded from ArrayExpress under the accession identifiers E-MTAB-3346 and E-MTAB-3624. The vignette of this data package provides a documented and reproducible workflow that includes the code that was used to generate each statistic and figure from the manuscript.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("Single.mTEC.Transcriptomes")

Details

MaintainerAlejandro Reyes <alejandro.reyes.ds@gmail.com>
AuthorAlejandro Reyes
LicenseLGPL
Downloads rank131
Source branchRELEASE_3_23
biocViewsExperimentData

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Dependencies

Depends: R (>= 3.5.0)

Suggests: DESeq2, GenomicRanges, GenomicFeatures, genefilter, statmod, gdata, RColorBrewer, ggplot2, gplots, cluster, clue, grid, gridExtra, ggbio, Gviz, geneplotter, matrixStats, pheatmap, BiocStyle, knitr, BiocParallel