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SiPSiC

Calculate Pathway Scores for Each Cell in scRNA-Seq Data

Bioconductor version: 3.23 · Package version: 1.12.0

Infer biological pathway activity of cells from single-cell RNA-sequencing data by calculating a pathway score for each cell (pathway genes are specified by the user). It is recommended to have the data in Transcripts-Per-Million (TPM) or Counts-Per-Million (CPM) units for best results. Scores may change when adding cells to or removing cells off the data. SiPSiC stands for Single Pathway analysis in Single Cells.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("SiPSiC")

Details

MaintainerDaniel Davis <DanielDavis000@gmail.com>
AuthorDaniel Davis [aut, cre] (ORCID: <https://orcid.org/0000-0001-7863-1521>), Yotam Drier [aut]
Licensefile LICENSE
URLhttps://www.genome.org/cgi/doi/10.1101/gr.278431.123
Bug Reportshttps://github.com/DanielDavis12/SiPSiC/issues
Downloads rank179
Source branchRELEASE_3_23
biocViewsBiomedicalInformatics, CellBiology, DataImport, DifferentialExpression, GeneSetEnrichment, ImmunoOncology, RNASeq, Sequencing, SingleCell, Software, Transcription, Transcriptomics

Documentation

Download

Dependencies

Depends: Matrix, SingleCellExperiment

Suggests: knitr, rmarkdown, BiocStyle

Reverse dependencies

Imports Me (1): GSABenchmark