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SPIAT

Spatial Image Analysis of Tissues

Bioconductor version: 3.23 · Package version: 1.14.0

SPIAT (**Sp**atial **I**mage **A**nalysis of **T**issues) is an R package with a suite of data processing, quality control, visualization and data analysis tools. SPIAT is compatible with data generated from single-cell spatial proteomics platforms (e.g. OPAL, CODEX, MIBI, cellprofiler). SPIAT reads spatial data in the form of X and Y coordinates of cells, marker intensities and cell phenotypes. SPIAT includes six analysis modules that allow visualization, calculation of cell colocalization, categorization of the immune microenvironment relative to tumor areas, analysis of cellular neighborhoods, and the quantification of spatial heterogeneity, providing a comprehensive toolkit for spatial data analysis.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("SPIAT")

Details

MaintainerYuzhou Feng <yuzhou0610@gmail.com>
AuthorAnna Trigos [aut] (ORCID: <https://orcid.org/0000-0002-5915-2952>), Yuzhou Feng [aut, cre] (ORCID: <https://orcid.org/0000-0002-2955-4053>), Tianpei Yang [aut], Mabel Li [aut], John Zhu [aut], Volkan Ozcoban [aut], Maria Doyle [aut]
LicenseArtistic-2.0 + file LICENSE
URLhttps://trigosteam.github.io/SPIAT/
Bug Reportshttps://github.com/trigosteam/SPIAT/issues
Downloads rank294
Source branchRELEASE_3_23
biocViewsBiomedicalInformatics, CellBiology, Clustering, DataImport, ImmunoOncology, QualityControl, SingleCell, Software, Spatial, Visualization

Documentation

Download

Dependencies

Depends: R (>= 4.2.0), SpatialExperiment (>= 1.8.0)

Imports: apcluster (>= 1.4.7), ggplot2 (>= 3.2.1), gridExtra (>= 2.3), gtools (>= 3.8.1), reshape2 (>= 1.4.3), dplyr (>= 0.8.3), RANN (>= 2.6.1), pracma (>= 2.2.5), dbscan (>= 1.1-5), mmand (>= 1.5.4), tibble (>= 2.1.3), grDevices, stats, utils, vroom, dittoSeq, spatstat.geom, methods, spatstat.explore, raster, sp, SummarizedExperiment, rlang

Suggests: BiocStyle, plotly (>= 4.9.0), knitr, rmarkdown, pkgdown, testthat, graphics, alphahull, Rtsne, umap, ComplexHeatmap, elsa