RTN
RTN: Reconstruction of Transcriptional regulatory Networks and analysis of regulons
Bioconductor version: 3.23 · Package version: 2.36.0
A transcriptional regulatory network (TRN) consists of a collection of transcription factors (TFs) and the regulated target genes. TFs are regulators that recognize specific DNA sequences and guide the expression of the genome, either activating or repressing the expression the target genes. The set of genes controlled by the same TF forms a regulon. This package provides classes and methods for the reconstruction of TRNs and analysis of regulons.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("RTN") Details
| Maintainer | Mauro Castro <mauro.a.castro@gmail.com> |
| Author | Clarice Groeneveld [ctb], Gordon Robertson [ctb], Xin Wang [aut], Michael Fletcher [aut], Florian Markowetz [aut], Kerstin Meyer [aut], and Mauro Castro [aut] |
| License | Artistic-2.0 |
| URL | http://dx.doi.org/10.1038/ncomms3464 |
| Downloads rank | 519 |
| Source branch | RELEASE_3_23 |
| biocViews | GeneExpression, GeneRegulation, GeneSetEnrichment, GeneticVariability, GraphAndNetwork, Network, NetworkEnrichment, NetworkInference, Software, Transcription |
Documentation
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Dependencies
Depends: R (>= 3.6.3), methods
Imports: RedeR, minet, viper, mixtools, snow, stats, limma, data.table, IRanges, igraph, S4Vectors, SummarizedExperiment, car, pwr, pheatmap, grDevices, graphics, utils
Suggests: RUnit, BiocGenerics, BiocStyle, knitr, rmarkdown
Reverse dependencies
Depends On Me (3): Fletcher2013b, RTNduals, RTNsurvival
Suggests Me (1): geneplast