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PAST

Pathway Association Study Tool (PAST)

Bioconductor version: 3.23 · Package version: 1.28.0

PAST takes GWAS output and assigns SNPs to genes, uses those genes to find pathways associated with the genes, and plots pathways based on significance. Implements methods for reading GWAS input data, finding genes associated with SNPs, calculating enrichment score and significance of pathways, and plotting pathways.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("PAST")

Details

MaintainerThrash Adam <thrash@igbb.msstate.edu>
AuthorThrash Adam [cre, aut], DeOrnellis Mason [aut]
LicenseGPL (>=3) + file LICENSE
URLhttps://github.com/IGBB/past
Bug Reportshttps://github.com/IGBB/past/issues
Downloads rank322
Source branchRELEASE_3_23
biocViewsGeneSetEnrichment, Pathways, Software

Documentation

Download

Dependencies

Depends: R (>= 4.0)

Imports: stats, utils, dplyr, rlang, iterators, parallel, foreach, doParallel, qvalue, rtracklayer, ggplot2, GenomicRanges, S4Vectors

Suggests: knitr, rmarkdown