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OmnipathR

OmniPath web service client and more

Bioconductor version: 3.23 · Package version: 4.0.0

A client for the OmniPath web service (https://www.omnipathdb.org) and many other resources. It also includes functions to transform and pretty print some of the downloaded data, functions to access a number of other resources such as BioPlex, ConsensusPathDB, EVEX, Gene Ontology, Guide to Pharmacology (IUPHAR/BPS), Harmonizome, HTRIdb, Human Phenotype Ontology, InWeb InBioMap, KEGG Pathway, Pathway Commons, Ramilowski et al. 2015, RegNetwork, ReMap, TF census, TRRUST and Vinayagam et al. 2011. Furthermore, OmnipathR features a close integration with the NicheNet method for ligand activity prediction from transcriptomics data, and its R implementation `nichenetr` (available only on github).

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("OmnipathR")

Details

MaintainerDenes Turei <turei.denes@gmail.com>
AuthorAlberto Valdeolivas [aut] (ORCID: <https://orcid.org/0000-0001-5482-9023>), Denes Turei [cre, aut] (ORCID: <https://orcid.org/0000-0002-7249-9379>), Attila Gabor [aut] (ORCID: <https://orcid.org/0000-0002-0776-1182>), Diego Mananes [aut] (ORCID: <https://orcid.org/0000-0001-7247-6794>), Aurelien Dugourd [aut] (ORCID: <https://orcid.org/0000-0002-0714-028X>)
LicenseMIT + file LICENSE
URLhttps://r.omnipathdb.org/
Bug Reportshttps://github.com/saezlab/OmnipathR/issues
Downloads rank1865
Source branchRELEASE_3_23
biocViewsAnnotation, DataImport, DataRepresentation, GeneRegulation, GeneSignaling, GraphAndNetwork, KEGG, Network, Pathways, SingleCell, Software, SystemsBiology, ThirdPartyClient, Transcriptomics

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Dependencies

Depends: R (>= 4.0)

Imports: checkmate, crayon, curl, digest, dplyr (>= 1.1.0), fs, httr2, igraph, jsonlite, later, logger, lubridate, magrittr, progress, purrr, rappdirs, readr (>= 2.0.0), readxl, rlang, rmarkdown, RSQLite, R.utils, rvest, sessioninfo, stats, stringi, stringr, tibble, tidyr, tidyselect, tools, utils, vctrs, withr, XML, xml2, yaml, zip

Suggests: BiocStyle, bookdown, ggplot2, ggraph, gprofiler2, knitr, mlrMBO, parallelMap, ParamHelpers, R.matlab, SBMLR, sigmajs, smoof, testthat

Reverse dependencies

Imports Me (3): gINTomics, MetaProViz, wppi

Suggests Me (2): decoupleR, dorothea