OUTRIDER

OUTRIDER - OUTlier in RNA-Seq fInDER

Bioconductor version: 3.23 · Package version: 1.30.0

Identification of aberrant gene expression in RNA-seq data. Read count expectations are modeled by an autoencoder to control for confounders in the data. Given these expectations, the RNA-seq read counts are assumed to follow a negative binomial distribution with a gene-specific dispersion. Outliers are then identified as read counts that significantly deviate from this distribution. Furthermore, OUTRIDER provides useful plotting functions to analyze and visualize the results.

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("OUTRIDER")