NewWave

Negative binomial model for scRNA-seq

Bioconductor version: 3.23 · Package version: 1.22.0

A model designed for dimensionality reduction and batch effect removal for scRNA-seq data. It is designed to be massively parallelizable using shared objects that prevent memory duplication, and it can be used with different mini-batch approaches in order to reduce time consumption. It assumes a negative binomial distribution for the data with a dispersion parameter that can be both commonwise across gene both genewise.

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("NewWave")