NBAMSeq

Negative Binomial Additive Model for RNA-Seq Data

Bioconductor version: 3.23 · Package version: 1.28.0

High-throughput sequencing experiments followed by differential expression analysis is a widely used approach to detect genomic biomarkers. A fundamental step in differential expression analysis is to model the association between gene counts and covariates of interest. NBAMSeq a flexible statistical model based on the generalized additive model and allows for information sharing across genes in variance estimation.

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("NBAMSeq")