MutSeqR
Analysis of Error-Corrected Sequencing Data for Mutation Detection
Bioconductor version: 3.23 · Package version: 1.0.0
Standard methods for analysis of mutation data following error- corrected sequencing (ECS) for the purpose of mutagencity assessment. Functions include importing the mutation lists provided by a variant caller, and a set of analytical tools for statistical testing and visualization of mutation data; comparison to COSMIC and/or germline signatures; etc.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("MutSeqR") Details
| Maintainer | Matthew J. Meier <matthew.meier@hc-sc.gc.ca> |
| Author | Annette E. Dodge [aut] (ORCID: <https://orcid.org/0000-0002-0446-9055>), Andrew Williams [aut] (ORCID: <https://orcid.org/0000-0002-7637-7686>), Danielle P.M. LeBlanc [aut] (ORCID: <https://orcid.org/0000-0002-3847-8371>), David M. Schuster [aut] (ORCID: <https://orcid.org/0009-0001-6316-4358>), Elena Esina [aut] (ORCID: <https://orcid.org/0009-0002-3443-378X>), Clint C. Valentine [aut] (ORCID: <https://orcid.org/0000-0001-5630-7368>), Jesse J. Salk [aut] (ORCID: <https://orcid.org/0000-0002-7804-0550>), Alexander Y. Maslov [aut], Christopher Bradley [aut], Carole L. Yauk [aut] (ORCID: <https://orcid.org/0000-0002-6725-3454>), Francesco Marchetti [aut] (ORCID: <https://orcid.org/0000-0002-9435-4867>), Matthew J. Meier [aut, cre] (ORCID: <https://orcid.org/0000-0001-8199-8754>), Geronimo Matteo [ctb] (ORCID: <https://orcid.org/0000-0003-0819-4471>), Health Canada's Genomics Research and Development Initiative [fnd], Canada Research Chairs Program [fnd] (CRC-2020-00060), Burroughs Wellcome Fund [fnd] |
| License | MIT + file LICENSE |
| URL | https://ehsrb-bsrse-bioinformatics.github.io/MutSeqR/ |
| Bug Reports | https://github.com/EHSRB-BSRSE-Bioinformatics/MutSeqR/issues |
| Downloads rank | 77 |
| Source branch | RELEASE_3_23 |
| biocViews | DriverMutation, GeneTarget, GenomicVariation, Sequencing, Software, SomaticMutation, StatisticalMethod, Visualization |
Documentation
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Dependencies
Depends: R (>= 4.5.0)
Imports: BiocGenerics, Biostrings, BSgenome, data.table, dplyr, GenomicRanges, ggplot2, here, IRanges, ggdendro, magrittr, methods, plyranges, rlang, S4Vectors, Seqinfo, stats, stringr, SummarizedExperiment, tibble, tidyr, utils, VariantAnnotation
Suggests: binom, BiocManager, BiocStyle, bs4Dash, BSgenome.Hsapiens.UCSC.hg38, BSgenome.Mmusculus.UCSC.mm10, car, colorspace, dendsort, doBy, DT, ExperimentHub, fmsb, fs, ggrepel, gtools, htmltools, httr, knitr, lme4, magick, MutSeqRData, openxlsx, packcircles, patchwork, RColorBrewer, reticulate, rmarkdown, scales, shiny, testthat (>= 3.0.0), trackViewer, withr, yaml, xml2